Endocrine Abstracts

Introduction: Acromegaly impairs the hypothalamic-pituitary-gonadal (HPG) axis and reproductive function that causes amenorrhea and infertility. The mechanism of these disturbances is not clear. Kisspeptin and neurokinin B are very important neuropeptides regulating cyclic LH release from pituitary due to stimulation of GnRH.Aim: The purpose of this study was to assess the role of key reproductive neuropeptides in regulation of menstrual function in pati...